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I have been taking Diovan for years for my blood pressure. Recently, it stopped working to keep the numbers down. I was 180-190/85 and began to take EForge, which was a combination of Diovan and a beta blocker. I got sick and my ankles swelled so badly they hung over my shoes. My doctor changed me to the hydrochlorothiazide along with the Diovan and it has worked wonderfully. There is a combination pill but I am afraid to take it because if I have a reaction then I have to stop both medicines, as happened with the EForge. No real problems with urination as I had expected.

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Irbesartan and hydrochlorothiazide tablets are indicated for the treatment of hypertension.

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You should avoid eating grapefruit and drinking grapefruit juice while taking Diovan.

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Food decreases the exposure (as measured by AUC) to valsartan by about 40% and peak plasma concentration (Cmax) by about 50%.

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